2. Signaling Pathways
  3. GPCR/G Protein
  4. Motilin Receptor
  5. Motilin Receptor Agonist

Motilin Receptor Agonist

Motilin Receptor Agonists (6):

Cat. No. Product Name Effect Purity
  • HY-P1037
    Motilin (26-47), human, porcine
    		Agonist
    Motilin (26-47), human, porcine is an endogenous motilin receptor ligand with Ki and EC50 of 2.3 nM and 0.3 nM in a Chinese hamster ovary cell line.
  • HY-144401
    DS-3801b
    		Agonist 99.18%
    DS-3801b is a potent and non-macrolide agonist of GPR38. DS-3801b is expected to be novel gastrointestinal prokinetic agents for the research of functional gastrointestinal disorders such as gastroparesis and chronic constipation.
  • HY-106323
    [Leu13]-Motilin
    		Agonist
    [Leu13]-Motilin (KW-5139) is a motilin analogue. [Leu13]-Motilin stimulates gastrointestinal motility in the rabbit. [Leu13]-Motilin causes concentration-dependent contractions of the gastric antrum, duodenum, jejunum, ileum and the descending colon in vitro.
  • HY-105263
    EM574
    		Agonist
    EM574 is a potent motilin receptor agonist in the human gastric antrum and rabbit gastrointestinal tract in vitro. EM574 is an erythromycin derivative.
  • HY-P3680
    [Nle13]-Motilin
    		Agonist
    [Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist.
  • HY-106258
    Atilmotin
    		Agonist
    OHM 11638 (Atilmotin), an analogue of the (1-14) fragment of porcine motilin, is a motilin receptor agonist with a pKd of 8.94 for the motilin receptor. OHM 11638 affects esophageal, lower esophageal sphincter (LES), and gastric motility. OHM 11638 increases LES and gastric pressures, OHM 11638 can be used as prokinetic agents.